Evidence in support of a causal association between night shift work and stomach ulcers. In this study the association with night shift work was moderate to strong but there was no attempt to identify which aspect of night shift work, or associated lifestyle choices, could provide a mechanism. Night shift work is of increasing prevalence, H Pylori infection is very common.
Evidence from:
A Pietroisti et al. Occ Env Med (2006) Vol.63 p 773-775
“Shift work increases the frequency of duodenal ulcer in H pylori infected workers”
The prevalence of duodenal ulcer was higher in night shift workers than in day time workers; 29% vs. 9%. Odds ratio = 3.9 (95% CI = 2.1 to 7.5).
Further detail: