This academic research investigated a proposed link between manifest allergy and death from cardiovascular disease. Allergy status was prospectively determined using a battery of skin-prick tests.
Evidence from:
PJ Gergen et al. Clinical and Experimental Allergy December (2000) Vol. 30 p.1717.
If allergy was a risk factor for fatal disease then those which should be controlled e.g. occupational allergens, could give rise to liabilities. Data from research such as this could provide a prospective estimate of the case load.
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